Case 2 question 2

Which of the following would you most likely obtain from her diarrhea work up?
Elevated stool bile acids
Correct! The patient has most likely developed bile acid diarrhea after limited ileal resection ( <150cm). Bile acids are reabsorbed in the terminal ileum and enter the enterohepatic circulation. In a patient who has had ileal resection with colon in continuity, there is impaired reabsorption of bile acids, which then enter the colon and cause a choleretic or secretory diarrhea
Elevated fecal calprotectin
Incorrect, Try again! She is unlikely to have elevated calprotectin since her CRP and CTE are normal, and the inflammed part of her small bowel and colon have been resected.
stool osmolar gap of 150mosm/Kg
Try again! Stool osmolar gap > 100mosm/kg indicates an osmotic diarrhea. Bile acid diarrhea is a secretory diarrhea
Elevated fecal fat
Incorrect, try again! Patients who have large ileal resection (>200cm) have a depleted bile acid pool. This causes fat malabsorption and steatorrhea, which would be diagnosed by elevated fecal fat levels.

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